Mitigation of Ionizing Radiation-induced Bone Marrow Suppression by p38 Inhibition and G-CSF Administration
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منابع مشابه
Mitigation of ionizing radiation-induced bone marrow suppression by p38 inhibition and G-CSF administration.
p38 mitogen-activated protein kinases (p38) has been shown to be activated in hematopoietic stem and progenitors cells after exposure to ionizing radiation (IR) and its activation has been implicated in bone marrow (BM) suppression under various pathological conditions. Therefore, in the present study we investigated whether inhibition of p38 activity alone with SB203580 (SB, a specific p38 inh...
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ژورنال
عنوان ژورنال: Journal of Radiation Research
سال: 2011
ISSN: 0449-3060,1349-9157
DOI: 10.1269/jrr.11007